Magyar
Csaba Kerepesi
I am the prinicpal investigator of the BioAgeAI and the HUN-REN-SZTAKI-SU Rejuvenation research groups. My research focuses to mathematics and informatics that can help against diseases and aging.
- Address: HUN-REN SZTAKI, Lágymányosi u. 11., 1111 Budapest, Hungary
- Contact: kerepesi (at) sztaki.hu, +36 1 279 6154
- Profiles: Google Scholar, MTMT, Linkedin.
- CV: Curriculum Vitae
Publication list
2026:- Unfried M, Huai W, Pabis K, Jose S, Meng ZL, Alon U, Cvijovic M, Eynon N, Fedichev P, Kim Y, Whye LK, Kerepesi C, Koh W-P, Kriukov D, Kaeberlein M, Ling F, Pridham G, Rera M, Rulands S, Rutenberg A, Selvarajoo K, Shenhar B, Scheibye-Knudsen M, Tarkhov AE, Teschendorff A, Wang W, Yong EH, Yang Y, Gruber J, Kennedy BK
Foundations of Gerophysics
Aging, (2026) [PDF], Q2
- Toth B, Mesterházi M, Szabo I, Mersich T, Toth E, Szoke J, Benczur A, Kerepesi C, Tarnoki DL,
Tarnoki AD
Magnetic resonance imaging based radiomics for predicting pathogenetic features and survival in rectal cancer
Pathology & Oncology Research, (2026) [PDF], Q2
- Nasser S, Keringer J, Gu Y, Boldogh I, Ba X, Higuchi M, Kerepesi C, Radak Z
Physical Fitness Is Negatively Associated With DNA Methylation-Based Risk of Aging-Related Diseases
Aging Cell, (2026) [PDF], D1
- Bárdos-Deák B, Király B, Kerepesi C
Improving face age prediction by using multiple-angle photos
Computational and Structural Biotechnology Journal, (2026) [PDF], D1
- Muralidharan C, Zakar-Polyák E, Adami A, Abbas AA, Sharma Y, Garza R, Johansson JG, Atacho DAM, Renner É, Palkovits M, Kerepesi C, Jakobsson J, Pircs K
Human Brain Cell-Type-Specific Aging Clocks Based on Single-Nuclei Transcriptomics
Advanced Science, Vol 12, Issue 43, e061092025 (2025) [PDF], D1
- Kawamura T, Kerepesi C, Sarkar JP, Torma F, Bori Z, Zhou L, Bakonyi P, Kolonics A, Balogh L, Higuchi M, Pillár V, Pircs K, Koch LG, Britton SL, Koltai E, Radak Z
Organ Specificity and Commonality of Epigenetic Aging in Low- and High-Running Capacity Rats
Aging Cell, Vol 24, Issue 8, e70110 (2025) [PDF], D1
- Farkas G, El Mahdaouy Z, Babszky G, Jokai M, Torma F, Gu Y, Pinho R, Miklossy I, Gordevicius J, Benczúr A, Kerepesi C, Radak Z
Associations of epigenetic aging and COVID‑19: A 3‑year longitudinal study
Geroscience, Vol 47, pages 4889–4898 (2025) [PDF], D1
- Kovács KA, Kerepesi C, Rapcsák D, Madaras L, Nagy Á, Takács A, Dank M, Szentmártoni Gy, Szász AM, Kulka J, Tőkés AM
Machine learning prediction of breast cancer local recurrence localization, and distant metastasis after local recurrences
Scientific Reports, 15, 4868 (2025) [PDF], Q1
- Radák Z, Aczél D, Fejes I, Mozaffaritabar S, Pavlik G, Komka Z, Balogh L, Babszki Z, Babszki G, Koltai E, McGreevy KM, Gordevicius J, Horvath S, Kerepesi C
Slowed epigenetic aging in Olympic champions compared to non-champions
GeroScience, Vol 47, pages 2555–2565 (2025) [PDF], D1
- Gladyshev VN et al.
Disagreement on foundational principles of biological aging
PNAS Nexus, (2024) [PDF], D1
- Zakar-Polyák E, Csordas A, Pálovics R, Kerepesi C
Profiling the transcriptomic age of single-cells in humans
Communications Biology, 7:1397 (2024) [PDF] , D1
- Castro JP, Shindyapina AV, Barbieri A, Ying K, Strelkova OS, Paulo JA, Tyshkovskiy A, Meinl R, Kerepesi C, Petrashen AP, Mariotti M, Meer MV, Hu Y, Karamyshev A, Losyev G, Galhardo M, Logarinho E, Indzhykulian AA, Gygi SP, Sedivy JM, Manis JP, Gladyshev VM
Age-associated clonal B cells drive B cell lymphoma in mice
Nature Aging, Vol 13 (2024) [PDF], C1
- Torma F, Kerepesi C, Jókai M, Babszki G, Koltai E, Ligeti B, Kalcsevszki R, McGreevy KM, Horvath S, Radák Z
Alterations of the gut microbiome are associated with epigenetic age acceleration and physical fitness
Aging Cell, Volume 23, Issue 4 (2024) [PDF], D1
- Kerepesi C, Abushukair HM, Ricciuti B, Nassar AH, Adib E, Alessi JV, Pecci F, Rakaee M, Fadlullah MZH, Tőkés A-M, Rodig SJ, Awad MM, Tan AC, Bakacs T, Naqash AR
Association of Baseline Tumor-Specific Neoantigens and CD8+ T-Cell Infiltration With Immune-Related Adverse Events Secondary to Immune Checkpoint Inhibitors
JCO Precision Oncology, Vol 8 (2024) [PDF], D1
- Juhász V, Ország A, Balla D, Szabó L, Sydó N, Kiss O, Csulak E, Babity M, Dohy Z, Skoda R, Becker D, Merkely B, Benczúr A, Vágó H, Kerepesi C
Blood Test-Based age Acceleration Is Inversely Associated with High-Volume Sports Activity
Medicine & Science in Sports & Exercise, 56(5):p 868-875 (2024), D1
- Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Hooten NN, Mitchell JR, Evans MK, Gladyshev VN & Sinclair DA
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction
Nature Aging, Vol 4, pages 261–274 (2024) [PDF], C1
- Szatmári E-Z, Csordás A, Kerepesi C
Unique Patterns in Amino Acid Sequences of Aging-Related Proteins
Advanced Biology, Volume 8, Issue 2 (2023) [PDF], Q1
- Kerepesi C, Gladyshev VN
Intersection clock reveals a rejuvenation event during human embryogenesis
Aging Cell, Vol 22, Issue 10 (2023) [PDF], D1
- Sturm Á, Saskői É, Hotzi B, Tarnóci A, Barna J, Bodnár F, Sharma H, Kovács T, Ari E, Weinhardt N, Kerepesi C, Perczel A, Ivics Z, Vellai T
Downregulation of transposable elements extends lifespan in Caenorhabditis elegans
Nature Communications 14, 5278 (2023) [PDF], D1
- Zhang B, Lee DE, Trapp A, Tyshkovskiy A, Lu AT, Bareja A, Kerepesi C, McKay LK, Shindyapina AV, Dmitriev SE, Baht GS, Horvath S, Gladyshev VN, White JP
Multi-omic rejuvenation and life span extension on exposure to youthful circulation
Nature Aging, Vol 3, pages 948–964 (2023) [PDF], C1
- Jokai M, Torma F, McGreevy KM, Koltai E, Bori Z, Babszki G, Bakonyi P, Gombos Z, Gyorgy B, Aczel D, Toth L, Osvath P, Fridvalszky M, Teglas T, Posa A, Kujach S, Olek R, Kawamura T, Seki Y, Suzuki K, Tanisawa K, Goto S, Kerepesi C, Boldogh I, Ba X, Davies KJA, Horvath S, Radak Z
DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation
Geroscience, Vol 45, 2805–2817 (2023) [PDF], D1
- Poganik JR, Zhang B, Baht GS, Kerepesi C, Yim SH, Lu AT, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, White JP, Horvath S, Gladyshev VN
Biological age is increased by stress and restored upon recovery
Cell Metabolism, 35, 1-14. (2023) [PDF], C1
- Kerepesi C, Meer MV, Ablaeva J, Amoroso VG, Lee S-G, Zhang B, Gerashchenko MV, Trapp A, Yim SH, Lu AT, Levine ME, Seluanov A, Horvath S, Park TJ, Gorbunova V, Gladyshev VN
Epigenetic aging of the demographically non-aging naked mole-rat
Nature Communications, 13, 355 (2022) [PDF], D1
- Nyéki A, Daróczy B, Kerepesi C, Neményi M, Kovács AJ
Spatial Variability of Soil Properties and Its Effect on Maize Yields within Field—A Case Study in Hungary
Agronomy, Vol 12, No. 395 (2022) [PDF], Q1
- Zhang B, Trapp A, Kerepesi C, Gladyshev VN
Emerging rejuvenation strategies—Reducing the biological age
Aging Cell, Volume 21, Issue 1 (2021) [PDF], D1
- Trapp A, Kerepesi C, Gladyshev VN
Profiling epigenetic age in single cells
Nature Aging, Vol 1, pages 1189–1201 (2021) [PDF]
- Khera N, Santesmasses D, Kerepesi C, Gladyshev VN
COVID-19 mortality rate in children is U-shaped
Aging, Vol 13, Issue 16, pp 19954—19962 (2021) [PDF], Q2
- Nyéki A, Kerepesi C, Daróczy B, Benczúr A, Milics G, Nagy J, Harsányi E, Kovács AJ, Neményi M
Application of spatio-temporal data in site-specific maize yield prediction with machine learning methods
Precision Agriculture, Vol 22, pp 1397–1415 (2021) [PDF], D1
- Kerepesi C, Zhang B, Lee SG, Trapp A, Gladyshev VN
Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging
Science Advances, Vol 7, Issue 26 (2021) [PDF], D1
- Santesmasses D, Castro JP, Zenin AA, Shindyapina AV, Gerashchenko MV, Zhang B, Kerepesi C, Yim SH, Fedichev PO, Gladyshev VN
COVID-19 is an emergent disease of aging
Aging Cell, Volume 19, Issue 10 (2020) [PDF], D1
- Kerepesi C, Bakacs T, Moss RW, Slavin S, Colin CA
Significant association between tumor mutational burden and immune‑related adverse events during immune checkpoint inhibition therapies
Cancer Immunology, Immunotherapy, Vol 69, pp 683–687 (2020) [PDF], D1
- Nyéki A, Kerepesi C, Daróczy B, Benczúr A, Milics G, Kovács AJ, Neményi M
Maize yield prediction based on artificial intelligence using spatio-temporal data
Precision agriculture '19 (2019) [PDF]
- Kerepesi C, Bakács T, Szabados T
MiStImm: an agent-based simulation tool to study the self-nonself discrimination of the adaptive immune response
Theoretical Biology and Medical Modelling, 16:9 (2019) [PubMed] [PDF], Q2
- Szalkai B, Kerepesi C, Varga B, Grolmusz V
High-Resolution Directed Human Connectomes and the Consensus Connectome Dynamics
PLOS ONE, 14(4):e0215473 (2019) [PubMed] [PDF], D1
- Mendik P, Dobronyi L, Hári F, Kerepesi C, Maia-Moço L, Buszlai D, Csermely P, Veres DV
Translocatome: a novel resource for the analysis of protein translocation between cellular organelles
Nucleic Acids Research, Volume 47, Issue D1 (2019). [PubMed] [PDF], D1
- Kerepesi C, Daróczy B, Sturm Á, Vellai T, Benczúr A
Prediction and characterization of human ageing-related proteins by using machine learning
Scientific Reports, Vol 8, 4094 (2018). [PubMed] [PDF], D1
- Kerepesi C, Varga B, Szalkai B, Grolmusz V
The Dorsal Striatum and the Dynamics of the Consensus Connectomes in the Frontal Lobe of the Human Brain
Neuroscience Letters 673:51-55 (2018). [PubMed], Q3
- Kerepesi C, Szalkai B, Varga B, Grolmusz V
Comparative connectomics: Mapping the inter-individual variability of connections within the regions of the human brain
Neuroscience Letters, Vol 662, pp 17-21, (2018). [PubMed], Q3
- Kerepesi C, Szalkai B, Varga B, Grolmusz V
The braingraph.org database of high resolution structural connectomes and the brain graph tools
Cognitive Neurodynamics, Vol 11, Issue 5 (2017). [PubMed] [PDF], Q3 - Kerepesi C, Grolmusz V
The "Giant Virus Finder" Discovers an Abundance of Giant Viruses in the Antarctic Dry Valleys
Archives of Virology, Vol 162, Issue 6, pp 1671–1676 (2017). [PubMed] [PDF], Q1 - Kerepesi C
Data Mining in Genomics, Metagenomics and Connectomics
PhD Thesis (2017). [PDF] - Bakacs T, Kristóf K, Mehrishi J, Szabados T, Kerepesi C, Regoes E, Tusnady G
Autoimmune T-cells induced by low dose immune checkpoint blockade could be a powerful therapeutic tool in cancer through activation of eliminative inflammation and immunity
Internal Medicine Review, Vol 3, No 4 (2017). [PDF] - Szabó A, Korponai K, Kerepesi C, Somogyi B, Vörös L, Bartha D, Márialigeti K, Felföldi T
Soda pans of the Pannonian steppe harbor unique bacterial communities adapted to multiple extreme conditions
Extremophiles, Vol 21, Issue 3 (2017). [PubMed] [PDF], Q2 - Szalkai B, Kerepesi C, Varga B, Grolmusz V
Parameterizable Consensus Connectomes from the Human Connectome Project: The Budapest Reference Connectome Server v3.0
Cognitive Neurodynamics, 11(1), pp. 113-116, (2017). [PubMed] [PDF], Q3
- Kerepesi C, Szabó JE, Papp-Kádár V, Dobay O, Szabó D, Grolmusz V and Vertessy BG
Life without dUTPase
Frontiers in Microbiology, 7:1768 (2016). [PubMed] [PDF], Q1 - Kerepesi C, Szalkai B, Varga B, Grolmusz V
How to Direct the Edges of the Connectomes: Dynamics of the Consensus Connectomes and the Development of the Connections in the Human Brain
PLOS ONE, 11(6): e0158680 (2016). [PubMed] [PDF], D1 - Kerepesi C, Grolmusz V
Evaluating the Quantitative Capabilities of Metagenomic Analysis Software
Current Microbiology, Vol 72, Issue 5, pp 612-616 (2016). [PubMed] [PDF], Q2 - Kerepesi C, Grolmusz V
Giant viruses of the Kutch Desert
Archives of Virology, Vol 161, Issue 3, pp 721-724 (2016). [PubMed] [PDF], Q1
- Szalkai B, Kerepesi C, Varga B, Grolmusz V
The Budapest Reference Connectome Server v2.0
Neuroscience Letters, Vol 595, pp 60–62 (2015). [PubMed], Q2 - Kerepesi C, Szalkai B, Grolmusz V
Visual Analysis of the Quantitative Composition of Metagenomic Communities: the AmphoraVizu Webserver
Microbial Ecology, Vol 69, Issue 3, pp 695-697 (2015). [PubMed] [PDF], Q1
- Kerepesi C, Bánky D, Grolmusz V
AmphoraNet: The webserver implementation of the AMPHORA2 metagenomic workflow suite
Gene, Vol 533, Issue 2, pp 538-540 (2014). [PubMed], Q1